Aniracetam and Oxiracetam are two of the most common nootropics used to enhance memory and boost focus. As they are cognitive enhancers, they are usually taken by individuals who want to promote mental clarity and support brain function.
Most of the effects of these nootropic agents are similar; however, Oxiracetam is a bit more stimulatory and is considered to be better for focus enhancement and mental acuity. On the other hand, Aniracetam works better for social anxiety, mood enhancement, and stress relief. Nonetheless, not everyone experiences the same effects, and there is a high level of variability in the results of both drugs.
Aniracetam is one of the fastest growing Racetam nootropics after its parent compound Piracetam. It works by heightening focus and motivation, supporting memory formation and recall, enhancing mood, and reducing anxiety. Taking a dose between 500-1500 mg per day is safe. Because the drug is fat-soluble, it is absorbed by the stomach and can easily cross the blood-brain barrier. Oxiracetam, on the other hand, is water-soluble.
Aniracetam also works differently as compared to other racetams. Most racetams stimulate acetylcholine receptors, but Aniracetam works by stimulating both the AMPA receptors and the kainite glutamate receptors.
Clinically, Aniracetam has been used to treat senile dementia, Alzheimer’s disease, age-related cognitive decline, and other types of cerebrovascular disorders. Recent studies have also shown that it improves attention, reasoning, memory, and focus while enhancing and boosting mood and anxiety as well. The main difference between Aniracetam and other nootropics is its ability to relieve feelings of anxiety and stress.
The drug also improves auditory and visual perception, allowing individuals to focus and study for more extended periods of time without getting tired. The study also showed neuroprotective benefits along with significant improvements in neuroplasticity. Aniracetam only lasts for 1-2.5 hours, but the metabolites mediate its pharmacological effects last longer as most of them.
Oxiracetam is mostly taken by individuals who want a more powerful alternative to Piracetam. It works by boosting energy, heightening alertness, perception, and focus, reducing mental fatigue, and enhancing memory and analytical thinking. Taking a dose between 400-2400 mg per day is safe.
The drug has psychostimulant properties and promotes higher energy levels without causing restlessness or jitters in individuals. However, it is different from Aniracetam as it does not have any significant effects on anxiety, mood, or depression. It is only moderately stimulating and is not as powerful as Adderall.
Oxiracetam has shown to promote positive effects on spatial reasoning, logical thinking, problem-solving, cognitive energy, memory, and attention. It has also improved mental functionality, wakefulness, and speaking ability in patients with an age-related cognitive decline, multi-infarct dementia, and cerebrovascular disease. The nootropic increases blood flow to the brain and enhances glucose and oxygen uptake, increasing synthesis and acetylcholine. It also supports numerous processes associated with long-term memory formation, boosting memory function in healthy young adults. Although Oxiracetam shows many neuroprotective properties and benefits, the therapeutic benefits take a long time to fully manifest. There are also fewer clinical trials and research than Aniracetam. It is also less commercially popular than Aniracetam.