With our modern, fast-paced lifestyle finding time to sleep can be quite a bother for some people who want more time to do as much as they can. Others, however, can’t sleep no matter how hard they try. This leaves about 35% of the population sleep-deprived and fatigued.
Adrafinil, also known as Olmifron or CRL-40028 might be the supplement you need. It is a precursor to Modafinil, which is the most commonly available version of the drug and its primary purpose was to be used as a eugeroic to promote wakefulness among patients suffering from daytime sleeping disorders. Adrafinil can also be used as a nootropic to enhance cognitive functions by helping users focus on tasks by giving them a clear mind.
History of origin
Adrafinil was first discovered in 1974 by Lafon Laboratories while they were searching for analgesics. Scientists discovered signs of hyperactivity in animals. However, the same effect was not observed in humans. Adrafinil was then put forward as an option in the treatment of narcolepsy because of its psychostimulant effects, i.e., wakefulness and cognitive enhancement. You can, therefore, use the supplement to energize you without the fear of going overboard.
Narcolepsy- This refers to a sleep disorder. It is often characterized by excessive sleepiness, sleep paralysis and in some cases partial or total loss of muscle control.
During testing to determine Adrafinil’s mechanism in the body, Modanifil was discovered. Adrafinil, when ingested, traveled to the liver where it was broken down to Modafinil and then processed. When technology for directly synthesizing Modafinil as a pharmaceutical agent became available research into Adrafinil was widely discontinued and it pharmaceutical companies stopped developing it for clinical use.
How does Adrafinil work?
Adrafinil affects the adrenergic system which is a part of the nervous system that releases adrenaline. It increases levels of hypocretin in the body which in turn leads to an increase in the levels of Dopamine, Norepinephrine, and Histamine in the body.
Many experts deem a 300 mg daily Adrafinil dosage safe whereas others say that it is safe to reach up to 900 mg dosages on some occasions. If you have allergies, however, I would recommend that you start with some low dosages to test how your body may react to the supplement.
You may have noticed that Adrafinil’s safe dosage range is higher than Modafinil. This is because a massive chunk of Adrafinil is lost when it is broken down to Modafinil in the liver before it is absorbed into your system. This is why a few extra milligrams of Adrafinil is necessary.
• Improves mental and physical function
Enhances awareness and focus
• Reduces depression symptoms
• Improves reaction time
You should also be a bit more patient when taking Adrafinil for the first time because it takes a little more time to be absorbed into your bloodstream. This is because, as I mentioned above, Adrafinil had to be broken down in the liver and converted into Modafinil for it to give you the desired effects. Taking more pills a short period after the first dosage might cause you more harm than good. It is, therefore, reasonable to exercise safety first.
That aside, I would also like to put some points across:
• Adrafinil capsules in the market today may be marked as supplements, but that does not mean that you should take them according to your whim. Adrafinil is a relatively powerful nootropic which means that you should probably start with a low dosage of about two pills to give your body some time to adjust.
• Adrafinil should be taken on a two week on, one week off cycle to give your body some time to recover and ensure that it doesn’t take a toll on your system.
• Adrafinil can affect your liver. You should, therefore, be careful and not go overboard when taking this supplement and keep in mind that Adrafinil is not for long-term use.
• Sleep is essential for a healthy body, you should, therefore, invest more of your time in trying to get a good night’s sleep.
It is important to note that individual users will respond differently to Adrafinil. Some may notice mild side-effects while others may experience severe reactions that are serious enough to cause the users to discontinue its use.
It does not cause the same amount of CNS (Central Nervous System) stimulation as is of typical Amphetamines and it has a lower risk of withdrawal symptoms, addiction, and tolerance as compared to most other nootropic supplements. However, it has a higher risk of adverse effects as compared to other nootropic supplements with the common ones being;
• Anxiety- It increases dopamine and norepinephrine to improve psychomotor activity. For some people, an increase in certain neurotransmitters triggers feelings of anxiety. This can be, primarily, dangerous for people who have PTSD or other anxiety-related conditions.
• Headaches- This is one of the most commonly reported side-effects especially by users with a history of migraines. Many of the reported cases seem to be user dependent with an increased dosage leading to more severe headaches. This is thought to be caused by constricted blood vessels. You should, therefore, try using Aspirin or other supplements that might have vasodilation effects to try and minimize the side effect.
• Stomach pain- This is most likely a result of taking high dosages, however, some users may be coupled with stomach pain even if they are taking low doses. This may, therefore, mean that your liver has been compromised especially if the problem persists after a reduction in the amount of dosage. If the problem persists, you should see a doctor and have your liver checked.
• Itchiness and skin rashes- Adrafinil (and other related compounds) are known to release histamines throughout the body. These are known to cause a mild allergic reaction to some users. However, this may be severe for others. It is therefore quite crucial for you to discontinue its use and consult a doctor if the side effects persist and become more severe.
• Insomnia and a disrupted sleep pattern- Adrafinil was formulated to combat sleepiness. A disrupted sleep pattern, therefore, is to be expected among Adrafinil users especially when they take it too late in the day. Taking the doses early in the morning and reducing the amount of dosage taken can help tackle this problem.
• Appetite suppression- Any stimulate and eugeroic can cause appetite suppression. It is not precisely known why this happens, but it has been noted that an increase in the dosage directly leads to a reduction in the user’s appetite which is sure to lead to weight loss.
Adrafinil is very useful although my senses were not that heightened in my seven day period. However, I felt more focused and ready to work. I had a mild but a persistent headache about a day into the trial, and I also noticed a reduction in appetite which increased with an increase in dosage.
I, therefore, recommend this nootropic for people who want more time to accomplish more tasks although you should be wary of any side effects and discontinue if they become more severe. Here are some user experiences to help you further.